Opposing Effects of Alcohol on the Immune System PMC
PMNs produce a host of bacteria-killing (i.e., bactericidal) molecules (e.g., myeloperoxidase, defensins, azurophil-derived bactericidal factors, bactericidal permeability-increasing protein, cationic proteins, gelatinase, and lactoferrin). In addition, PMNs participate in the regulation of the local defense response by releasing signaling molecules called cytokines and chemokines (e.g., tumor necrosis factor [TNF]-α; interleukin [IL]-1β, IL-6, and IL-8; and macrophage […]